Gordene produces and co-hosts GenderTalk Radio, while also directing the Women's Studies program at Merrimack College in North Andover, Massachusetts. She recently taught an upper level seminar titled "Gender, Sex and Society: Public and Private Bodies" in the Honors Program at the University of New Mexico in Albuquerque, as well as courses on "Sociology of Gender" and "Sociology of Deviance" at Albuquerque's Technical Vocational Institute. Gordene founded the first transgender and cross-dresser support group in New Mexico in 1985 and co-directed the group and ran the TG help phone line for over seven years. In 1997, while serving as an assistant professor of Women's Studies, Gordene developed and taught the first transgender studies course offered at the University of New Mexico. She has been a visiting scholar at the University of Wyoming, an adjunct professor at Antioch University, a freelance editor, poet, hypnotherapist, and co-owner (and designer) of a jewelry business in Albuquerque for over 20 years. Gordene has been interviewed on many local and national radio and television programs. She helped direct a documentary on women and violence for public television.

In her spare time she writes poetry and, with her partner Nancy Nangeroni, created a short series of gender detective short stories about 2 transvestite/drag queens, one born female and one born male, who investigate gender crimes. She is also now beginning exploration of the activist and natural world through the viewfinder of a video camera, her first co-creation with Nancy a music video "In Memory of Rita" inspired by the candlelight vigil for a murdered transperson. She is also, in her copious free time, working on a book about the gender ambiguous body in US and international film.